How Low Dose Naltrexone Supports Mental Health: Anxiety, Depression & PTSD

Mental health challenges like anxiety, depression, and PTSD affect millions of people, and finding effective treatments can be a struggle. At A2Z RX, we’re always looking for promising therapies that go beyond the usual options. One such treatment gaining attention is Low Dose Naltrexone (LDN), particularly at doses like 4.5 mg. Though originally developed for addiction treatment, LDN’s unique properties are showing potential for mental health support — including anxiety, depression, and PTSD.

Naltrexone, in its standard dose, is commonly used to block opioid receptors in addiction care. But at low doses — usually between 1.5 mg and 4.5 mg — it acts differently. Low Dose Naltrexone temporarily blocks opioid receptors, which leads the body to increase its own production of endorphins and enkephalins. These natural chemicals help regulate mood, reduce pain, and support immune function. At A2Z RX, we provide access to Low Dose Naltrexone, including popular doses like LDN 4.5 mg, tailored to support both mental health and chronic pain conditions. Whether you’re seeking relief from autoimmune symptoms, fibromyalgia, or emotional distress, we’re here to help you discover if LDN is the right fit.